Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB)
Federal Resources on AMR

National Action Plan
National efforts to address antimicrobial resistance (AMR) span the entirety of the U.S. Government. These efforts are guided by the National Action Plan (NAP) for Combating Antibiotic-Resistant Bacteria (CARB). This foundational document is the roadmap of US federal CARB efforts and is updated every five years.
The CARB NAP is produced by the Office of the Assistant Secretary for Planning and Evaluation (ASPE), a division under the U.S. Department of Health and Human Services (DHHS). The CARB NAP is developed by the Federal Interagency CARB Task Force, which is a coalition of federal agencies across the One Health spectrum that have a stake in CARB. The Federal Interagency CARB Task Force works closely with the PACCARB to develop the CARB NAP in each of its five-year iterations. ASPE publishes the CARB NAP and produces the annual progress reports.
National Action Plan for Combating Antibiotic-Resistant Bacteria
Current CARB NAP, 2020-2025
Additional Federal Resources
DHHS, Office of the Assistant Secretary for Planning and Evaluation (ASPE)
ASPE advises the Secretary of the Department of Health and Human Services on policy development in health, disability, human services, data, and science; and provides advice and analysis on economic policy. ASPE houses the CARB NAP and all CARB progress reports.
Centers for Disease Control and Prevention (CDC)
CDC is the nation’s leading science-based, data-driven, service organization that protects the public’s health. CDC leads the U.S. public health response to combat antimicrobial resistance.
U.S. Department of Agriculture (USDA)
The USDA is responsible for protecting American agriculture and the American food supply. One of the many ways USDA does this is by addressing antimicrobial resistance.
Food and Drug Administration (FDA)
The FDA is responsible for protecting public health by ensuring the safety, efficacy, and security of human and veterinary drugs, biological products, and medical devices. The FDA helps to preserve the effectiveness of currently available antimicrobial drugs and promoting the development of new medical products.
Biomedical Advanced Research and Development Authority (BARDA)
BARDA invests in public-private partnerships to support the development of medical countermeasures to combat antimicrobial resistance.
National Institutes of Health (NIH)
The NIH conducts and supports research to improve the health of the Nation, and through the National Institute of Allergy and Infectious Diseases, the NIH funds research to combat antimicrobial resistance.
DHHS, Agency for Healthcare Research and Quality (AHRQ)
AHRQ is charged with improving the safety and quality of healthcare for all Americans. AHRQ develops knowledge, tools, and data to help combat antimicrobial resistance.
DHHS, Office of Global Affairs (OGA)
OGA is the diplomatic voice of the U.S. Department of Health and Human Services (DHHS), and works close with international partners to address antimicrobial resistance.
Content created by Assistant Secretary for Health (ASH)
Content last reviewed November 14, 2023