Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Preventive Medication

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Systematic Review

Source: U.S. Preventive Services Task Force

Last Reviewed: April 2018

The U.S. Preventive Services Task Force (USPSTF) recommends against daily supplements of 400 IU or less of vitamin D and 1000 mg or less of calcium for postmenopausal women. The USPSTF recommends against this supplementation for primary prevention of fractures in community-dwelling populations. There’s insufficient evidence to assess the benefits and harms for doses greater than 400 IU of vitamin D and 1000 mg of calcium. There’s also insufficient evidence to assess the benefits or harms of any supplement dosage for men and premenopausal women.

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U.S. Preventive Services Task Force. (2018). Vitamin D, calcium, or combined supplementation for the primary prevention of fractures in community-dwelling adults: Preventive medication. Retrieved from https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-adults-preventive-medication