About this resource:

HHS Non-systematic Review

Source: Agency for Healthcare Research and Quality

Last Reviewed: September 2012

This resource is a toolkit to help hospitals develop effective antimicrobial stewardship programs with the potential to reduce Clostridium difficile (C. difficile) infections. It helps organizations consider:

  • If they’re ready for an antimicrobial stewardship program
  • How to determine which interventions for reducing C. difficile to implement
  • How to monitor interventions and measure outcomes
  • How to sustain an antimicrobial stewardship program
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Suggested Citation


Luka, C.V., Koppelmen, E., Currie, B., Ostrowsky, B., Brown, S., Meissner, P.,...Gould, C. Evaluation and Research on Antimicrobial Stewardship's Effect on Clostridium difficile (ERASE C. difficile) Project: Toolkit for Reduction of Clostridium difficile Through Antimicrobial Stewardship (Publication 12-0082-EF). Retrieved from https://www.ahrq.gov/hai/patient-safety-resources/cdiff-toolkit/index.html