Syphilis Infection in Nonpregnant Adults and Adolescents: Screening

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Systematic Review

Source: U.S. Preventive Services Task Force

Last Reviewed: September 2022

The U.S. Preventive Services Task Force (USPSTF) recommends screening adults and adolescents who aren’t pregnant for syphilis infection if they’re at an increased risk for getting syphilis. This recommendation applies to adults and adolescents who have ever been sexually active — even if they don’t have symptoms. USPSTF found that treating syphilis with antibiotics can cure syphilis infections before they progress and cause lasting damage. Treatment also prevents people who have syphilis from passing it to other people.

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U.S. Preventive Services Task Force. (2022). Syphilis Infection in Nonpregnant Adults and Adolescents: Screening. Retrieved from https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/syphilis-infection-nonpregnant-adults-adolescents-screening