About this resource:

Systematic Review

Source: U.S. Preventive Services Task Force

Last Reviewed: November 2016

The U.S. Preventive Services Task Force (USPSTF) recommends that some adults without a history of cardiovascular disease (CVD) use a low- or moderate-dose statin to prevent CVD events and death. Specifically, the recommendation applies to people who:

  • Are ages 40 to 75 years
  • Have 1 or more CVD risk factors
  • Are at high risk for a CVD event

USPSTF found insufficient evidence to assess whether the benefits of starting statins outweigh the harms in people age 76 years or older without a history of CVD.

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Suggested Citation


U.S. Preventive Services Task Force. (2016). Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication. Retrieved from https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication