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Systematic Review

Source: The Cochrane Collaborative

Last Reviewed: April 2007

In this Cochrane systematic review, the Cochrane Collaborative found that psychotropic analgesic nitrous oxide (PAN) is as effective as sedatives for managing mild or moderate alcohol withdrawal. However, researchers noted that the review doesn’t offer strong evidence about the benefits or harms of using PAN instead of sedatives, so more research is needed. They also noted that the studies included in the review were conducted in inpatient settings but that PAN is also used in outpatient settings.

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Suggested Citation

1.

Gillman, M.A., Lichtigfeld, F. & Young, T. (2007). Psychotropic analgesic nitrous oxide for alcoholic withdrawal states. Cochrane Database of Systematic Reviews, 2007 (2). DOI: 10.1002/14651858.CD005190.pub2.