Management of Multidrug-Resistant Organisms Guidelines

About this resource:

HHS Non-systematic Review

Source: Centers for Disease Control and Prevention

Last Reviewed: February 2017

This set of guidelines offers recommendations
to help all health care providers prevent infections due to multidrug-resistant organisms (MDROs). It categorizes the recommendations by type, including:

  • Administrative measures
  • Education and training of health care personnel
  • Systems for effective treatment of infections and correct use of antibiotics 
  • Surveillance
  • Infection control precautions
  • Environmental measures

Prevention and control of MDROs requires both the leadership of administrators and scientific leaders and a commitment of financial and human resources.

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Suggested Citation


Siegel, J., Rhinehart, E., Jackson, M., Chiarello, L., and the Healthcare Infection Control Practices Advisory Committee. (2006). Management of Multidrug-Resistant Organisms in Healthcare Settings, 2006. Retrieved from