About this resource:
Source: Agency for Healthcare Research and Quality
Last Reviewed: 2020
In this systematic review, researchers examine evidence from over 260 studies to assess the effectiveness of interventions to prevent or delay age-related cognitive decline, mild cognitive impairment, and clinical Alzheimer’s-type dementia. Researchers found that most interventions showed no evidence of delaying or preventing dementia. They found some evidence that cognitive training can improve cognitive function for some older adults in the short term. Researchers also found that some types of physical activity, as well as vitamin B12 plus folic acid, may benefit cognitive performance in some older adults.
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Kane RL, Butler M, Fink HA, Brasure M, Davila H, Desai P, Jutkowitz E, McCreedy E, Nelson VA, McCarten JR, Calvert C, Ratner E, Hemmy LS, Barclay T. (2017). Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer's-Type Dementia. Comparative Effectiveness Review No. 188. Retrieved from https://effectivehealthcare.ahrq.gov/products/cognitive-decline/research-2017.