About this resource:

HHS Non-systematic Review

Source: Office of the Surgeon General

Last Reviewed: 2010

This Surgeon General’s report considers the biologic processes and the behaviors that lead  tobacco smoke to cause disease. It considers the evidence on whether specific processes are important in producing diseases caused by tobacco smoke. The evidence is important to:

  • Understand how smoking causes disease 
  • Identify susceptible people 
  • Assess possible risks of tobacco products 

The evidence is also relevant to achieving tobacco-related goals in the Healthy People initiative.

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Suggested Citation


U.S. Department of Health and Human Services, Office of Surgeon General. (2010). How Tobacco Smoke Causes Disease The Biology and Behavioral Basis for Smoking-Attributable Disease. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK53017/pdf/Bookshelf_NBK53017.pdf [PDF - 17.7 MB]