CDC, CPSC, and FDA
2004 to present
Mode of Collection
Surveillance data (passive data collection) collected at a sample of U.S. hospital emergency departments.
The National Electronic Injury Surveillance System – Cooperative Adverse Drug Event Surveillance Project (NEISS-CADES) is an expansion of the Consumer Product Safety Commission's (CPSC) National Electronic Injury Surveillance System (NEISS), used to monitor consumer-product related injuries. NEISS-CADES collects data on all adverse drug events (ADEs) treated in U.S. hospital emergency departments, whether or not associated with consumer products. NEISS data are collected from a nationally representative sample of U.S. hospital emergency departments; NEISS-CADES uses a subsample of those emergency departments for its data collection.
NEISS-CADES collects demographic data, diagnoses, drug data (name of medication, dose, concomitant medications), and tests and treatments performed in the emergency department.
U.S. civilian non-institutionalized population.
NEISS hospitals are a stratified probability sample of all U.S. hospitals that have at least 6 beds and provide 24- hour emergency department (ED) services. The NEISS-CADES data are collected at a subset of these hospitals and include very large inner-city hospitals with trauma centers, as well as large urban, suburban, rural, and children's hospitals. Trained onsite hospital coders abstract and code data for all cases of adverse drug events (ADEs) treated in the hospital ED. ADEs include allergic reactions, side effects, unintentional overdoses, secondary effects, nonmedical use, and self-harm. Injuries resulting solely from alcohol, tobacco, or illicit drug use are excluded. Data are weighted to produce national estimates.
Response Rates and Sample Size
NEISS collects data from a sample of 100 hospitals with 24 hour emergency department services. NEISS-CADES data are collected at 60 of these hospitals.
- Jhung MA, Budnitz DS, Mendelsohn AB, et al. Evaluation and Overview of the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance Project (NEISS-CADES). Medical Care. 2007;10(2):S96-S102.
- U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. Data and Statistics (WISQARS), Nonfatal Injury Data.